Estudios

Muchos estudios se han llevado adelante para demostrar los beneficios del colágeno en la salud. Entre las diversas bibliografías podemos encontrar las siguientes:

• Adam, M.  (1991). Welche Wirkung haben gelatinepräparate? Therapie der Osteoarthrose. Therapiewoche 41, Iss. 38, p.2456-2461.
• Adam, M. (1995). Gelatine Möglicher medizinischer einsatz. Apotheker Journal, Vol. 17, Iss. 9, p. 18 – 22.
• Appelt, K. (2005). Effekte der Gelatinesupplementierung auf den Knochen- und Knorpelstoffwechsel im Verlauf einees standardisierten Trainings beim Pferd. Inaugural Dissertation, Institut für Tierernährung, Tierärztliche Hochschule Hannover.
• Bello, A.E. and Oesser, S. (2006). Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature. Current Medical Research and Opinions, Vol. 22., Iss. 11, 2221-2232.
• Castro, G.A., Carvalho, J.E., Tinti, S.V., Possenti, A. and Sgarbieri, V.C. (2010). Anti-Ulcerogenic Effect of a Whey Protein Isolate and Collagen Hydrolysates Against Ethanol Ulcerative Lesions on Oral Administration to Rats. Journal of Medicinal Food, Vol. 13, Iss. 1, 83-90.
• Clark, K.L., Sebastianelli, W., Flechsenhar, K.R., Aukermann, D.F., Meza, F., Millard, R.L., Deitch, J.R., Sherbondy, P.S. and Albert, A. (2008). 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Current Medical Research and Opinions, Vol. 25, Iss. 5, 1485-1496.
• Fabien-Soulé, V. (2007). Oral intake of hydrolyzed collagen may stimulate collagen production by human cells themselves – literature review and results. 8^th Congress of the International Society of Cosmetic Dermatology, Bejing, China.
• Götz, B. (1982). Gut genährter knorpel knirscht nicht merh. Chondropathia patellae bei jugendlichen: stimulierung der knorpel-biosynthese bessert die symptome in 80% der fälle. Ärztliche Praxis, Vol. 34, Iss. 92, p. 3130 – 35.
• Guillerminet, F., Beaupied, H., Fabien-Soulé, V., Tomé, D., Benhamou, C.L., Roux, C. and Blais, A. (2009). Hydrolyzed collagen improves bone metabolism and biomechanical parameters in ovariectomized mice: an in vitro and in vivo study. Bone, published online 2009 Nov 3.
• Hata, S., Hayakawa, T., Okada, H., Hayashi, K., Akimoto, Y. And Yamamoto, H. (2008). Effect of oral administration of high advanced collagen tripeptide (HACP) on bone healing process in rat. Journal of Hard Tissue Biology, Vol. 17, Iss. 1, 17-22.
• Hydrolyzed bovine collagen
• Jellice Co., Ltd. – High Advanced Collagen Tripeptide
• Jerosch, J. (2010). Klinische Effekte einer Ernährungstherapie auf die Arthrosesymptomatik – Ergebnisse einer multizentrischen Beobachtungsstudie. Orthopädische Praxis, Vol 46, Iss. 2, 79-88.
• K. Seeligmüller und K.H. Happel (1993). Arthrosetherapie mit einer Gelatine/LCystin– Zubereitung Dem Knorpel auf die Sprünge helfen. Therapiewoche 43, Iss. 36, 1810 – 1813.
• Krug, E. (1979). Zur unterstützenden Therapie bei Osteo- und Chondropathien. Erfahrungsheilkunde Zeitschrift für die Ärtzliche Praxis, Vol 28, Iss. 28, 1-23.
• Lee, S.K., Posthauer, M.E., Dorner, B., Redovian, V. and  Maloney, J. (2006). Pressure ulcer healing with a concentrated fortified collagen protein hydrolysate supplement: a randomized controlled trial. Advances in Skin and
• Matsuda, N., Koyama, Y.-I., Hosaka, Y., Ueda, H., Watanabe, T., Araya, T., Irie, S. And Takehana, K. (2006). Effects of ingestion of collagen peptide on collagen fibrils and glycosaminoglycons in the dermis. Journal of Nutrition Science and Vitaminology, Vol. 52, 211-215.
• Minaguchi, J., Koyama, Y.-I., Meguri, N., Hosaka, Y., Ueda, H., Kusubata, M., Hirota, A., Irie, S., Mapune, N. and Takehana (2005). Effects of ingestion of collagen peptide on collagen fibrils and glycosaminoglycans in Achilles tendon. Journal of Nutritional Science and Vitaminology, Vol. 51, 169-174.
• Moskowitz, R.W. (2000). Role of collagen hydrolysate in bone and joint disease. Seminar Arthritis Rheum, Vol. 30, 87-99.
• Ng, K.W., Saliman, J.D., Kelly, T.AN., Statman, L.Y., Ateshian, G.A., Hung, C.T. (?). Collagen hydrolysate increases the mechanical properties and type II collagen synthesis of tissue engineered articular cartilage. Paper no: 0259, 51^st Annual Meeting of the Orthopaedic Research Society.
• Nippi pigskin  collagen hydrolysate (3000 – 5000 Da)
• Oberschelp, U. (1985). Individuelle Arthrosetherapie ist möglich. Therapiewoche, Vol. 44, 5094-5097.
• Oesser, S. And Seifert, J. (2003). Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen. Cell Tissue Research, Vol. 311, 393-399.
• Oesser, S., Adam, M., Babel, W. And Seifert, J. (1999). Oral administration of ¹⁴C labelled gelatin hydrolysate leads to an accumulation of radioactivity in cartilage of mice (C57/BL). The Journal of Nutrition, Vol. 129, 1891-1895.
• Olson, G.B., Savage, S. And Olson, J.-A. (2000). The effects of collagen hydrolysate on symptoms of chronic fibrmyalgia and temporomandibular joint pain. The Journal of Craniomandibular Practice, Vol. 18, Iss. 2, 135-141.
• Ruiz-Benito, P., Camacho-Zambrano, M.M., Carrillo-Arcentales, J.N., Mestanza-Peralta, M.A., Vallejo-Flores, C.A., Vargas-Lopez, S.V., Villacis-Tamayo, R.A. and Zurita-Gavilanes, L.A. (2009). A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort. International Journal of Food Sciences and Nutrition. Vol. 60, s2, 99-113.
• Seeligmüller, K. and Happel, K.H. (1989). Kann eine Gelatine/L-Cystin-mischung die Kollagen- und Proteoglykansynthese stimulieren? Therapiewoche, Vol. 39, 3153 – 3157.
• Swaim, S.F., Gillette, R.L., Sartin, E.A., Hinkle, S.H. and Coolman, S.L. (2000). Effects of a hydrolyzed collagen dressing on the healing of open wounds in dogs. AJVR, Vol. 61, Iss. 12, 1574-1578.
• Watanabe-Kamiyama, M., Shimizu, M., Kamiyama, S., Taguchi, Y., Sone, H., Morimatsu, F. And Komai, M. (2009). Absorption and effectiveness of orally administered low molecular weight collagen hydrolysate in rats. Journal of Agricultural and Food Chemistry, published online December 3.
• Weh, L. (1999). Gelatine: Are there any health potential? Extracta Orthopaedica, Vol. 22, Iss. 5, 15-17.
• Weh, L. And Petau, C. (2001). Change in the properties of tissue through the administration of gelatine A biomechanical in-vivo pilot study. Extracta Orthopaedica, Iss. 4 – 2001, 12-16.
• Weide, N. (2004). Der Einsatz von Gelatinehydrolysat bei klinisch-orthopädisch gesunden Hunden und Hunden mit chronischen Erkrankungen des Bewegungsapparates. Dissertation, Tierärztliche Hochschule Hannover.
• Wound Care, Vol. 19, Iss. 2, 92-96.
• Wu, J., Fujioka, M., Sugimoto, K., Mu, G. And Ishimi, Y. (2004). Assessment of effectiveness of oral administration of collagen peptide on bone metabolism in growing and mature rats. Journal of Bone and Mineral Metabolism, Vol. 22, 547-553.
• Yoichi, K., Arisa, S., Kumiko, K. and Masashi, K. (2006). Effects of oral ingestion of collagen peptide on the skin. Fragrance Journal, Vol. 34, Iss. 6, 82-85.
• Zague, V. (2008). A new view concerning the effects of collagen hydrolysate intake on skin properties. Archives of Dermatological Research, Vol. 300, 479-483.
• Zolotarev, Y.A., Badmaeva, K.E.,  Bakaeva, Z.V., Samonina, G.E., Kopylova, G.N., Dadayan, A.K., Zverkov, Y.B., Garanin, S.K., Vaskovsky, B.V., Ashmarin, I.P. and Myasoedov, N.F. (2006). Short peptide fragments with antiulcer activity from a collagen hydrolysate. Russian Journal of Bioorganic Chemistry, Vol. 32, Iss. 2, 174-178.